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Pathways Recommended: Cell Cycle/DNA Damage
Results for "

DNA Gyrase-IN-2

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

3

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0132S
    Norfloxacin-d5

    		Bacterial Antibiotic Infection
    Norfloxacin-d5 is the deuterium labeled Norfloxacin. Norfloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase[1][2].
    Norfloxacin-d5
  • HY-147818
    DNA Gyrase-IN-2

    		Bacterial DNA/RNA Synthesis Infection
    DNA Gyrase-IN-2 (Compound 22a) is a bacterial DNA gyrase B inhibitor with IC50s of 3.29-10.49 and 4.41-5.61 µM for E. coli DNA gyrase and M. tuberculosis DNA gyrase. Anti-tubercular and antibacterial activity .
    <em>DNA</em> <em>Gyrase-IN-2</em>
  • HY-147777
    14α-Demethylase/DNA Gyrase-IN-2

    		Bacterial DNA/RNA Synthesis Infection
    14α-Demethylase/DNA Gyrase-IN-2 (Compound 6a) is a potent inhibitor of 14α-Demethylase/DNA Gyrase. 14α-Demethylase/DNA Gyrase-IN-2 has antimicrobial activities .
    14α-Demethylase/<em>DNA</em> <em>Gyrase-IN-2</em>
  • HY-155007
    DNA gyrase B-IN-2

    		Bacterial Infection
    DNA gyrase B-IN-2 (Compound E) is a 2-aminobenzothiazole-based DNA gyrase B inhibitor with promising activity against ESKAPE bacterial pathogens. DNA gyrase B-IN-2 showed low nanomolar inhibition of DNA gyrase (IC50 < 10 nM) and broad-spectrum antibacterial activity against pathogens belonging to the ESKAPE group, with the minimum inhibitory concentration < 0.03 μg/mL for most Gram-positive strains and 4–16 μg/mL against Gram-negative E. coli, Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae.DNA gyrase B-IN-2 can be used for the research of infection .
    DNA <em>gyrase</em> B-IN-2
  • HY-W011117S
    Danofloxacin-d3

    		Isotope-Labeled Compounds Bacterial DNA/RNA Synthesis Infection
    Danofloxacin-d3 is deuterium labeled Danofloxacin. Danofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent. Danofloxacin shows a broad spectrum of activity against most Gram-negative and Gram-positive bacteria, mycoplasma and chlamydia species, and plays an antimicrobial role by inhibition of bacterial DNA-gyrase[1][2].
    Danofloxacin-d3
  • HY-W011117S1
    Danofloxacin-d3-1

    		Isotope-Labeled Compounds Others
    Danofloxacin-d3-1 is deuterium labeled Danofloxacin. Danofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent. Danofloxacin shows a broad spectrum of activity against most Gram-negative and Gram-positive bacteria, mycoplasma and chlamydia species, and plays an antimicrobial role by inhibition of bacterial DNA-gyrase .
    Danofloxacin-d3-1

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